Pharmaceutical Client




Two large air-handling systems providing air to an ISO 5 Sterile Filling Area were analyzed for reliability.

Air-Handling Unit Reliability Analysis

  • Fault Tree Analysis and Failure Mode and Effects Analysis (FMEA) were used to identify and quantify 53 different failure events. The goal was to address HVAC system shutdowns and issues with controlling cleanroom pressures.
  • GBA’s report provided 23 recommendations for improving reliability and reducing lost-production-time events. Strategies ranged from modifying differential pressure sensors and adding vertical louvers for snow and ice protection, to a variety of controls adjustments and addition/replacement of equipment.
  • The client also received an equipment report card estimating condition and service life of existing equipment.

View More Projects

Interested in learning more about how GBA can assist with your facility objectives? Our portfolio is a great place to start. 

Skyscraper board room

430 N. Michigan (Realtor Building)

A large-scale vertical expansion called on GBA's analytical, design, and commissioning skills.

Hallway with rehab equipment

Shirley Ryan AbilityLab, Pediatric & DayRehab Center

This outpatient center serves children and adults; GBA provided engineering design services for the adaptive reuse project.

Exterior of Todd Building, University of Kentucky

University of Kentucky, Lee T. Todd, Jr. Building

An ASHRAE Level 1 audit,  retro-commissioning, and a lab ventilation assessment improved sustainability.